How Polyunsaturated Fats Lower Cholesterol?

The prevailing evidence suggests that the decrease in plasma low-density lipoprotein cholesterol induced by polyunsaturated fat is a result of modified secretion of cholesteryl ester (in the case of n-6 fatty acids) and triglyceride (in the case of n-3 fatty acids) and increased low-density lipoprotein receptor ...

How does polyunsaturated fat affect cholesterol?

Polyunsaturated fats can help lower your LDL (bad) cholesterol. Cholesterol is a soft, waxy substance that can cause clogged or blocked arteries (blood vessels). Having low LDL cholesterol reduces your risk for heart disease. Polyunsaturated fats include omega-3 and omega-6 fats.

How does PUFA lower cholesterol?

PUFA-rich diets repress the transcription of lipogenic genes by suppressing SREBP-1 gene transcription or by reducing the maturation of SREBP-1 protein, thereby reducing the levels of MUFAs, TGs, and cholesterol esters in plasma and liver.

James H. Sterling

James H. Sterling

Environmental Science & Climate Journalist

James Sterling reports on renewable energy developments, climate policy, ecological conservation, and green tech innovations around the globe.