How to Synthesize Chalcone?

Synthesis. Chalcones can be prepared by an aldol condensation between benzaldehyde and acetophenone in the presence of sodium hydroxide as a catalyst. This reaction can be carried out without any solvent as a solid-state reaction.

Which is the best method of synthesizing chalcone?

Chalcones are synthesized by conventional and microwave assisted synthesis methods. By microwave assisted synthesis, a considerable increase in the reaction rate has been observed and that too, with better yields.

How chalcone products are purified?

Each chalcone is then isolated by suction filtration after washing with water. Although the crude chalcone is often found to have sufficient purity for product characterization, recrystallization is performed with 95% ethanol to remove trace impurities.