In Acquired Immunological Tolerance?

Burnet developed the concept that the immune system develops predicicted that it would be experimentally possible to fool a body into believing that a foreign substance was 'self'. The mice were said to have 'aquired immunological tolerance' to a particular tissue. ...

What are the types of immunological tolerance?

Immunologic tolerance occurs in two forms: central and peripheral. Table 14.1 compares central and peripheral immunologic tolerance with respect to B cell and T cell participation, positive and negative selection, clonal anergy, clonal deletion, etc.

Who discovered immunological tolerance?

Medawar and his co-workers showed that tolerance can be experimentally induced in fetal mice and in chick embryos. In 1960, Medawar in recognition of the significance of his 1953 and 1956 papers was awarded the Nobel Prize in Physiology or Medicine with Burnet for their discovery of acquired immunologic tolerance.

Alexander Ross

Alexander Ross

Gaming, Esports & Interactive Media Writer

Alexander Ross has covered the video game industry for a decade, writing deep dives on game design, esports tournaments, VR developments, and gaming culture.