In Double Stranded Dna?

Double-stranded DNA consists of two polynucleotide chains whose nitrogenous bases are connected by hydrogen bonds. Within this arrangement, each strand mirrors the other as a result of the anti-parallel orientation of the sugar-phosphate backbones, as well as the complementary nature of the A-T and C-G base pairing.

What happens in double stranded DNA?

Double-strand breaks in DNA can be lethal to a cell. ... By-products of the cell's own metabolism such as reactive oxygen species can damage DNA bases and cause lesions that can block progression of replication. The result is double-strand breaks (DSBs) in the chromosome.

What does it mean to have double stranded DNA positive?

A positive result for double-stranded DNA (dsDNA) IgG antibodies in the appropriate clinical context is suggestive of systemic lupus erythematosus (SLE).