In Insulin-Stimulated Glucose Uptake?

Insulin stimulates glucose transport into these tissues by causing the recruitment, or translocation, of GLUT4 proteins from an intracellular vesicular compartment to the plasma membrane. Once GLUT4 recruitment occurs, the transporter inserts into the plasma membrane, allowing uptake of glucose into the cell.

Where does insulin stimulate glucose uptake?

The effect of insulin to acutely stimulate glucose uptake into muscle and adipose tissue is essential for normal glucose homeostasis. The GLUT4 glucose transporter is a major mediator of this action, and insulin recruits GLUT4 from an intracellular pool to the plasma membrane.

What is stimulated glucose uptake?

Insulin-stimulated glucose uptake involves the transition of glucose transporters to a caveolae-rich fraction within the plasma membrane: implications for type II diabetes.