In the Upstream Process?

Upstream process is the first step of bioprocess from early cell isolation and cultivation, to cell banking and culture development of the cells until final harvest where the desired quantity is reached. Since this is the early stage of bioprocessing, the quality of the product is of critical importance.

What is upstream in a process?

The upstream process is defined as the entire process from early cell isolation and cultivation, to cell banking and culture expansion of the cells until final harvest (termination of the culture and collection of the live cell batch).

What are the steps in upstream processing?

Upstream processing involves all the steps related with inoculum development: Media Preparation, Cell Culture and Cell Separation & Harvest. When the cells have reached the desired density, they are harvested and moved to the downstream section of the bioprocess.

Maya Lin-Takahashi

Maya Lin-Takahashi

Consumer Tech & Gadget Reviewer

Maya is a hardware enthusiast who tests and reviews smart home devices, smartphones, wearables, and audio gear. She focuses on practical consumer value and build quality.