Increase in Monoamine Oxidase?
Calcium (Ca2+) Has Recently Been Shown to Selectively Increase the Activity of Monoamine Oxidase-a (Mao-A), a Mitochondria-Bound Enzyme That Generates...
Calcium (Ca2+) has recently been shown to selectively increase the activity of monoamine oxidase-A (MAO-A), a mitochondria-bound enzyme that generates peroxyradicals as a natural by-product of the deamination of neurotransmitters such as serotonin.
What does a monoamine oxidase do?
An enzyme called monoamine oxidase is involved in removing the neurotransmitters norepinephrine, serotonin and dopamine from the brain. MAOIs prevent this from happening, which makes more of these brain chemicals available to effect changes in both cells and circuits that have been impacted by depression.
What is high Mao?
An advanced monoamine theory (Figure 3A-D) can be conceptualized: During an MDE, elevated MAO-A levels increase the metabolism of monoamines such as serotonin, norepinephrine, and dopamine. Thereafter, individual monoamine transporter densities have a secondary influence on specific extracellular monoamine levels.
James Sterling reports on renewable energy developments, climate policy, ecological conservation, and green tech innovations around the globe.
