Is Bromadiolone Harmful to Dogs?

The “second-generation” anticoagulants (brodifacoum, bromadiolone, difethiolone) are highly toxic to nontarget species (dogs, cats, livestock, or wildlife) after a single feeding. Secondary poisoning in nontarget animal species from anticoagulants has also been documented.

What happens if my dog eats bromadiolone?

Signs of poisoning in dogs can include bleeding from the mouth and nose, internal bleeding, bruising, bloody urine and stool, hypothermia, depression, lack of appetite, muscle weakness and pain, difficulty breathing, seizures, coma, and death.

How much bromadiolone is lethal to dogs?

Based on clinical cases, the minimum toxic dose is 0.5-3 mg/kg and the minimum lethal dose is 4.5 mg/kg. Real life cases differ dramatically from the technical LD₅₀ of 88 mg/kg in the dog. The trigger dose for treatment in the dog is greater than or equal to 0.1 mg/kg.