Is Digoxin Removed by Dialysis?

Hemodialysis is not effective for digoxin removal as a result of the tremendous tissue distribution of the drug at steady state, which is only approximately 0.5% in the blood.

Is digoxin dialyzed out?

In patients with kidney failure, neither digoxin nor Fab can be removed efficiently from the systemic circulation by hemodialysis or continuous arteriovenous hemofiltration.

Is digoxin cleared by kidney?

Digoxin pharmacokinetics Digoxin is predominantly cleared unchanged by the kidneys, although small amounts are also cleared by other routes. In patients with normal renal function, the elimination half- life is around 36 hours.