Is Leptin a Adipokine

Leptin is a pleiotropic adipokine with diverse effects on cell types throughout the body. Its role in neuroendocrine signaling, homeostasis, and metabolism has been well studied.

What type of hormone is leptin?

Leptin is a peptide hormone synthesized by white adipose tissue. The leptin gene (LEP or ob) is on chromosome 7q31. 3. [2] The mature protein is comprised of 146 amino acids and produced through mRNA-directed protein synthesis.

Is leptin an Adipocytokine?

LEP is the first adipocytokine identified and discovered in 1994 by Friedman and Halaas [52, 53]. It is a 167-amino acid protein including a 21 amino acid signal peptide.