Is Nystatin a Polyene?

Nystatin is a polyene macrolide antibiotic produced by Streptomyces noursei ATCC 11455 and used in human therapy for treatment of topical fungal infections.

What are polyene antibiotics?

The polyene antibiotics comprise a class of molecules that are toxic to fungi but not to bacteria. They are produced by the bacteria Streptomyces. Although there are many polyene antibiotics (Kinsky, 1967) only three are used clinically to treat fungal infections — nystatin, amphotericin B, and candicidin.

What are the two classes of polyene antifungal?

The polyene antifungal agents include nystatin, amphotericin B, and pimaricin.