Is Oligomycin an Uncoupler?
The Inhibitors of H+-Atp-Synthase Oligomycin (5 Μg/Ml) and Aurovertin B (10 Μm) Was Shown to Strongly Suppress, and Uncoupler (0.1 mM Dnp) Stimulates, the Cell...
The inhibitors of H+-ATP-synthase oligomycin (5 μg/ml) and aurovertin B (10 μM) was shown to strongly suppress, and uncoupler (0.1 mM DNP) stimulates, the cell respiration, indicating that it is tightly coupled to ATP synthesis (Figure 1).
What type of inhibitor is oligomycin?
Oligomycin is a specific inhibitor of the ATPase and blocks proton translocation leading to a hyperpolarization of the inner mitochondrial membrane.
What are Uncouplers give example?
The following compounds are known to be classical uncouplers: 2,4-dinitrophenol (DNP) ... 2-tert-butyl-4,6-dinitrophenol (Dinoterb) 6-sec-butyl-2,4-dinitrophenol (Dinoseb)
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