Is Tetrahydroxypropyl Ethylenediamine Safe?

Safety testing using a repeat insult patch testing of a formulation containing THPE in 220 subjects revealed no incidence of irritation or sensitization, indicating that topical THPE was safe to use on skin.

What is tetrahydroxypropyl ethylenediamine?

Tetrahydroxypropyl ethylenediamine (THPE) is an ingredient used as a chelating agent; it is found in cosmetics, sunscreens, anti-aging products, moisturizers, and several other personal care products. It has infrequently been the cause of allergic contact dermatitis (ACD).

What is Neutrol TE?

Description. Neutrol® TE is a reaction product of ethylenediamine with 4 moles of propylene oxide. This gel is formulated with the feature high alcohol compatibility to stimulate a pleasant, nonsticky sensation on the skin. It is used for the manufacture of soap and stearate cremes.

Sarah Jenkins

Sarah Jenkins

Senior Technology Editor & AI Specialist

Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.