Is There a Word Despite?

Despite is used as a preposition when something happens even though it might have been prevented by something else. You might go see a movie despite hearing a review calling it worse than Ishtar. ... The phrase "in despite of" gradually got shortened to the preposition despite and lost its scornful quality.

Is there such a word as despite?

: in spite of The quarterback played despite an injury.

Is it correct to say despite of?

Despite means the same as in spite of. Don't say `despite of'. Despite the difference in their ages, they were close friends. The school is going to be closed despite protests from local people.