Is Translocated into the Nucleus?
Nuclear Protein Import Is a Selective Process. .. . Following Binding at the Pore Complex, Proteins Are Translocated Through the Pore into the Nucleus in a...
Nuclear protein import is a selective process. ... Following binding at the pore complex, proteins are translocated through the pore into the nucleus in a manner requiring ATP. The biochemical dissection of the
How are proteins delivered to the nucleus?
Nuclear proteins are transported actively through nuclear pores by a selective, mediated process. The process is mediated by a nuclear localization signal (NLS), and can be divided into at least two steps, (a) targeting to the pores and (b) translocation through the pores.
What moves from the cytoplasm into the nucleus?
Transport of RNAs
Whereas many proteins are selectively transported from the cytoplasm into the nucleus, most RNAs are exported from the nucleus to the cytoplasm. Since proteins are synthesized in the cytoplasm, the export of mRNAs, rRNAs, and tRNAs is a critical step in gene expression in eukaryotic cells.