What Are Dermal Papilla Cells

Abstract. Hair dermal papilla cells are specialized mesenchymal cells that exist in the dermal papilla located at the bottom of hair follicles. These cells play pivotal roles in hair formation, growth, and cycling.

What is the dermal papilla and what is its function?

The dermal papilla functions as a signaling center during initial hair morphogenesis in the embryo, as well as during the adult hair cycle. The dermal papilla transmits signals to the surrounding epithelium, maintaining its proliferation and differentiation into the various cell types of the growing hair shaft.

What is the dermal papilla made of?

The dermis contains dermal papillae and reticular. Hair follicles and sweat glands reside between these layers. Papillae is composed of thick collagen fibers whereas the reticular layer, situated near the surface of the skin, is formed from a thin and delicate fibers.