What Are Mutations and How Can They Affect Proteins
A frameshift mutation is one that will most likely cause a change in the protein’s structure and function.

Which type of point mutation had no effect on the resulting protein why?

A silent mutation does not affect the functioning of the protein. A single nucleotide can change, but the new codon specifies the same amino acid, resulting in an unmutated protein. This type of change is called synonymous change since the old and new codon code for the same amino acid.

Which of the following mutations is most likely to be disruptive to protein synthesis or function?

Frameshift mutations are much more disruptive to the genetic code than simple base substitutions, because they involve a base insertion or deletion, thus changing the number of bases and their positions in a gene. For example, the mutagen proflavine causes frameshift mutations by inserting itself between DNA bases.

James H. Sterling

James H. Sterling

Environmental Science & Climate Journalist

James Sterling reports on renewable energy developments, climate policy, ecological conservation, and green tech innovations around the globe.

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