What Blood Tests Show Scleroderma?

Antinuclear antibody (ANA) testing is the most important blood test to screen for scleroderma and other connective tissue diseases.

What labs are abnormal with scleroderma?

Blood tests: Elevated levels of immune factors, known as antinuclear antibodies, are found in 95% of patients with scleroderma. Although these antibodies are also present in other autoimmune diseases such as lupus, testing for them in potential scleroderma patients is helpful in assisting with an accurate diagnosis.

Can a blood test detect scleroderma?

A blood test alone cannot diagnose scleroderma. Depending on the clinical situation, additional tests may be done, such as: Pulmonary function tests or breathing tests to measure how well the lungs are working. CT chest scan may also be ordered to evaluate the extent of lung involvement.