What Can Explode in Your Stomach?

When your stomach is filled with too much stuff and you don't vomit, all of that mass gets pushed up against the stomach's walls and can lead to it rupturing.

Is it possible for your stomach to explode?

Yes, you can "explode" your stomach from eating too much. You probably won't, but the possibility exists. The average human stomach holds about 1 liter's-worth of contents. You might have heard that the stomach can shrink or stretch, and to a certain degree that's true.

What happens if your stomach ruptures?

When the stomach ruptures, a hole is formed. This open hole lets out the stomach contents into the abdominal cavity where it results in infection and requires surgical intervention. The medical term for this is gastrointestinal perforation, and it's almost always not caused simply by overeating.