What Causes Dariers Disease
The Linear Form of Darier Disease Is Caused by Atp2A2 Gene Mutations That Are Acquired During a Person’s Lifetime and Are Present Only in Certain Cells. These...
The linear form of Darier disease is caused by ATP2A2 gene mutations that are acquired during a person’s lifetime and are present only in certain cells. These changes are called somatic mutations and are not inherited.
What triggers Darier's disease?
Darier disease is caused by mutations in the ATP2A2 gene . This gene gives the body instructions to make an enzyme known as SERCA2. This enzyme helps control the level of calcium ions inside cells .
Is Darier's disease life threatening?
Initial misdiagnosis of keratosis follicularis (Darier disease) may lead to undertreatment of such infections and may lead to fatal outcomes. However, overall, patients with keratosis follicularis (Darier disease) have a life expectancy similar to that of the general population.
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