What Causes Margination

When the gap size between the cell surface and the wall becomes larger than the thickness of RBCs, margination is caused by overtaken or overtaking events.

What is Margination of a cell?

To facilitate the adhesion, white blood cells migrate toward the vessel walls in blood flow through a process called margination. … In addition, aggregation interactions between red blood cells lead to enhanced white-blood-cell margination.

What is Margination and Pavementing?

Margination- Normally red and white cells flow intermingled in the center of the vessel separated from vessel wall by a clear cell-free plasmatic zone. – Due to slowing of the circulation, leucocytes fall out of the. axial stream and come to periphery known as margination. • Pavementing- neutrophils close to vessel …