What Causes Xanthochromia in Csf
Xanthochromia Is a Yellow, Orange, or Pink Discoloration of the Csf, Most Often Caused by the Lysis of Rbcs Resulting in Hemoglobin Breakdown to Oxyhemoglobin...
Xanthochromia is a yellow, orange, or pink discoloration of the CSF, most often caused by the lysis of RBCs resulting in hemoglobin breakdown to oxyhemoglobin, methemoglobin, and bilirubin. Discoloration begins after RBCs have been in spinal fluid for about two hours, and remains for two to four weeks.
What does Xanthochromic CSF mean?
Xanthochromia, from the Greek xanthos (ξανθός) “yellow” and chroma (χρώμα) “colour”, is the yellowish appearance of cerebrospinal fluid that occurs several hours after bleeding into the subarachnoid space caused by certain medical conditions, most commonly subarachnoid hemorrhage.
How long does it take for xanthochromia to develop?
Therefore, xanthochromic CSF at the time of LP indicates SAH; however, xanthochromia can take as long as 12 hours to develop (19), and delaying an LP for that long after ictus to ensure its appearance may be unacceptable.
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