What Diseases Cause Splenomegaly?

Causes
  • Viral infections, such as mononucleosis.
  • Bacterial infections, such as syphilis or an infection of your heart's inner lining (endocarditis)
  • Parasitic infections, such as malaria.
  • Cirrhosis and other diseases affecting the liver.

What is the most common cause of splenomegaly?

Infections, such as mononucleosis, are among the most common causes of splenomegaly. Problems with your liver, such as cirrhosisand cystic fibrosis, can also cause an enlarged spleen. Another possible cause of splenomegaly is juvenile rheumatoid arthritis. This condition can cause inflammation of the lymph system.

What diseases cause enlarged spleen?

What causes an enlarged spleen?
  • Viral, fungal and bacterial infections.
  • Hemolytic anemia, in which the spleen destroys healthy red blood cells.
  • Blood clots of the veins from the spleen or liver.
  • Liver diseases, including cirrhosis.
  • Cancers, such as leukemia and lymphoma.
Elena Rostova

Elena Rostova

Lead Health, Wellness & Medical Journalist

Elena Rostova holds a Master's degree in Public Health Journalism. She covers groundbreaking medical research, holistic wellness trends, mental health awareness, and nutritional science.