What Do Chondrocytes Do?
Chondrocytes in the Ac Proliferate and Secrete Extracellular Matrix to Maintain and Sustain the Cartilage. the Cells Themselves Are Separated from Each Other...
Chondrocytes in the AC proliferate and secrete extracellular matrix to maintain and sustain the cartilage. The cells themselves are separated from each other by cartilage matrix [2]. They respond to outside stimuli and tissue damage, and are also responsible for degenerative conditions, such as osteoarthritis (OA).
What are the function of chondrocytes?
Chondrocytes are the cells responsible for cartilage formation, and they are crucial for the process of endochondral ossification, which is useful for bone development. Also, by mimicking skeletal development chondrocytes play a critical role in fracture repair.
What is the role of chondrocytes in bone formation?
The canonical pathway of the endochondral bone formation process involves apoptosis of hypertrophic chondrocytes followed by vascular invasion that brings in osteoclast precursors to remove cartilage and osteoblast precursors to form bone.
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