What Do Macrophages Sensitize?

Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression. Cell Rep.

What do macrophages stimulate?

Macrophages are stimulated by the low oxygen content of their surroundings to produce factors that induce and speed angiogenesis and they also stimulate cells that re-epithelialize the wound, create granulation tissue, and lay down a new extracellular matrix.

How do macrophages work?

Macrophages work as innate immune cells through phagocytosis and sterilization of foreign substances such as bacteria, and play a central role in defending the host from infection. However, residual macrophages in intestinal mucosa can potentially reduce inflammation to a greater extent than those in other tissues.