What Does Bupropion Do to the Brain?

Wellbutrin, also known as bupropion, is one of the more commonly prescribed antidepressants. The drug is a norepinephrine-dopamine reuptake inhibitor, or NDRI. Basically, the medication alters a person's mood by increasing dopamine levels in the brain.

Does bupropion cause brain damage?

Bupropion overdose is associated with a clinical examination demonstrating the absence of brainstem reflexes and the lack of a meaningful motor response, the combination of which can be suggestive of brain death in the proper clinical setting.

What part of the brain does bupropion effect?

These results demonstrate that treatment with bupropion is associated with an improved ability to resist cue-induced craving and a reduction in cue-induced activation of limbic and prefrontal brain regions.