What Does Cardiazol Mean?
Pentylenetetrazol, Also Known as Pentylenetetrazole, Metrazol, Pentetrazol, Pentamethylenetetrazol, Corazol, Cardiazol, Deumacard, or Ptz, Is a Drug Formerly...
Pentylenetetrazol, also known as pentylenetetrazole, metrazol, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, Deumacard, or PTZ, is a drug formerly used as a circulatory and respiratory stimulant.
What is Pentylenetetrazol used for?
Pentylenetetrazol has been used experimentally to study seizure phenomena and to identify pharmaceuticals that may control seizure susceptibility. For instance, researchers can model status epilepticus in animal models.
What is PTZ seizure?
Abstract. Pentylenetetrazole (PTZ) is a GABA-A receptor antagonist. An intraperitoneal injection of PTZ into an animal induces an acute, severe seizure at a high dose, whereas sequential injections of a subconvulsive dose have been used for the development of chemical kindling, an epilepsy model.