What Does Extra Articular Mean?

Extra-articular means outside of or other than a joint. RA affects your joints, as well as other systems in your body. Therefore, you can also call these manifestations or effects systemic.

What is extra-articular involvement?

Extra-articular manifestations are all the conditions and symptoms which are not directly related to the locomotor system (2,4,5). Extra-articular RA is a serious condition, and rheumatoid arthritis patients with extra-articular manifestations should be aggressively treated and monitored (6).

What is the difference between extra-articular and intra-articular?

An extra-articular fracture features a break above the wrist joint; the fracture does not extend into the joint itself. Intra-articular fractures are wrist fractures that affect the wrist joint. The distal radius is fractured, including the joint.