What does ISO mean in NBA 2k20?

ISO is short for isolation. In a game of basketball, where you at least have one other teammate, you can do an iso play. You and the person guarding you are in a 1v1, essentially, even when you both have 4 teammates. You two are literally isolated, with the other players virtually out of the way.

Who is the best iso player in the NBA?

5 best isolation players in the 2020-21 NBA season
  • Five best isolation players in the NBA.
  • #5 Giannis Antetokounmpo – 28.4 points.
  • #4 Luka Doncic – 28.6 points per game.
  • #3 Kyrie Irving – 26.8 points per game.
  • #2 Damian Lillard – 28.4 points per game.
  • #1 James Harden – 25.2 points per game.