What Does It Mean to Be Preload Dependent

As mentioned in the article,1 preload dependence is defined as a state in which increases in right ventricular and/or left ventricular end-diastolic volume

Why is RV preload dependent?

Like the LV, contraction of the RV is preload dependent at normal physiologic filling pressures, and excessive RV filling can result in a shift of the septum towards the LV and ventricular interdependence causing impaired LV function.

How does preload affect the body?

Increased preload increases stroke volume, whereas decreased preload decreases stroke volume by altering the force of contraction of the cardiac muscle. The concept of preload can be applied to either the ventricles or atria.

Alexander Ross

Alexander Ross

Gaming, Esports & Interactive Media Writer

Alexander Ross has covered the video game industry for a decade, writing deep dives on game design, esports tournaments, VR developments, and gaming culture.

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