What Happens During Luteinization?

Luteinization is essential to the success of early gestation. It is the process by which elements of the ovarian follicle, usually including both theca interna

theca interna
Theca interna cells express receptors for luteinizing hormone (LH) to produce androstenedione, which via a few steps, gives the granulosa the precursor for estrogen manufacturing. After rupture of the mature ovarian follicle, the theca interna cells differentiate into the theca lutein cells of the corpus luteum.
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and granulosa cells, are provoked by the ovulatory stimulus to develop into the corpus luteum.

What is Luteinization of granulosa cells?

Introduction. Following ovulation, granulosa cells (GC) undergo a process of luteinization which involves cell enlargement and increased progesterone production. These luteinized GC eventually form the dominant progesterone-producing layer of the corpus luteum (see review by Behrman et al., 1993).

What do ovarian follicles do?

Ovarian follicles are small sacs filled with fluid that are found inside a woman's ovaries. They secrete hormones which influence stages of the menstrual cycle and women begin puberty with about 300,000 to 400,000 of them. Each has the potential to release an egg for fertilisation.

Sarah Jenkins

Sarah Jenkins

Senior Technology Editor & AI Specialist

Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.