What Is a Syngeneic Model?

A syngeneic mouse model, also known as an allograft mouse tumor system, provides an effective approach for studying how cancer therapies perform in the presence of a functional immune system.

What is a syngeneic mouse model?

What is a syngeneic mouse model? Syngeneic mouse models, also known as Allograft mouse tumor systems, consist of tumor tissues derived from the same genetic background as a given mouse strain. As the syngeneic mice retain intact immune systems, they are particularly relevant for studies of immunotherapies.

What is the meaning of syngeneic?

(SIN-jeh-NAY-ik) Having to do with individuals or tissues that have identical genes. For example, identical twins and cells and tissues from them are syngeneic.