What Is an Efflux?

All microorganisms, with a few exceptions, have highly conserved DNA sequences in their genome that are transcribed and translated to efflux pumps.

What is efflux in biology?

Efflux is the process in which bacteria transport compounds outside the cell which are potentially toxic, such as drugs or chemicals or compounds.

What is efflux of antibiotics?

Drug efflux is a key mechanism of resistance in Gram-negative bacteria. These systems pump solutes out of the cell. Efflux pumps allow the microorganisms to regulate their internal environment by removing toxic substances, including antimicrobial agents, metabolites and quorum sensing signal molecules.