What Is Aniline Acetylation

Aniline or phenylamine is a primary amine and basic in nature. … Aniline reacts with acetic anhydride to form Acetanilide by nucleophilic substitution reaction and the reaction is called acetylation. In this reaction, aniline acts as the nuclepohile and acyl (CH3CO-) group from acetic anhydride acts as the electrophile.

Why do we do aniline acetylation?

Acetylation is often used to place an acetyl protecting group on primary or secondary amines to reduce their reactivity toward oxidizing agents or electrophiles.

What is the acetylation process?

Acetylation is a reaction that introduces an acetyl functional group (acetoxy group, CH3CO) into an organic chemical compound—namely the substitution of the acetyl group for a hydrogen atom—while deacetylation is the removal of an acetyl group from an organic chemical compound.