What Is Bulkier Group?

Alexander Ross
Alexander Ross
• • 6 min read

A Bulky Group Can Block a Position. It Can Also Change the Shape Such That Only One Diastereomer from a Reaction Is Made. Steric Effects Steric Effects Steric...

What Is Bulkier Group?

A bulky group can block a position. It can also change the shape such that only one diastereomer from a reaction is made. Steric effects

Steric effects
Steric hindrance is the slowing of chemical reactions due to steric bulk. ... Steric hindrance is often exploited to control selectivity, such as slowing unwanted side-reactions. Steric hindrance between adjacent groups can also affect torsional bond angles.
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are usually smaller than electronic effects. These affect the molecule's shape and reactivity as well, but they come from the way electrons are placed in bonds.

Are phenyl groups bulky?

I agree, generally speaking the phenyl group is considered a rather large substituent. One metric commonly used to compare "steric size" is the cyclohexane A-Value. In the cyclohexane ring system, bulky substituents prefer the equatorial position rather than the axial position.

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Is OCH3 a bulky group?

Our teacher told us that OCH3 is a less bulky group when compared to other bulky groups like CH3, NO2 etc.

Alexander Ross

Alexander Ross

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