What Is Circumferential Resection Margin?

Circumferential resection margin(CRM) is the closest distance from the deepest of tumor invasion to the surgical margin of mesentery. It has been well known that CRM has significant impact on the prognosis and treatment of rectal cancer.

What does circumferential resection margin mean?

INTRODUCTION. Circumferential resection margin (CRM) is the closest distance between the radial resection margin and the tumor tissue by either direct tumor spread, areas of neural or vascular invasion, or the nearest involved lymph node.

What does CRM-positive mean?

CRM involvement was defined as a distance from the circumference margin of ≤1 mm. 9. Patients were divided into two groups: "CRM-positive group" (CRM ≤1 mm) and "CRM-negative group" (CRM >1 mm) according to the shortest distance between the CRM and the tumor (Fig. 1).

James H. Sterling

James H. Sterling

Environmental Science & Climate Journalist

James Sterling reports on renewable energy developments, climate policy, ecological conservation, and green tech innovations around the globe.