What Is Decoy Sequence?

Alexander Ross
Alexander Ross
• • 6 min read

Answer: the Hs38D1 Decoy Contains Dna Viral Sequences (E. G. Epstein-Barr Virus) as Well Human Genomic Human Genomic the Human Genome Is a Complete Set of...

What Is Decoy Sequence?

Answer: The hs38d1 decoy contains DNA viral sequences (e.g. Epstein-Barr Virus) as well human genomic

human genomic
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. ... Human genomes include both protein-coding DNA genes and noncoding DNA.
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sequence that could not be placed on chromosomes when the reference genome was put together. Much of the decoy consists of repeats that are difficult to assemble.

What is a decoy genome?

The decoy is a pragmatic solution to this - it contains known true human genome sequence that is not in the reference genome, and will "suck up" reads that would otherwise map with low quality in the reference.

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What is a decoy aware transcriptome?

There are two options for generating a decoy-aware transcriptome: The first is to compute a set of decoy sequences by mapping the annotated transcripts you wish to index against a hard-masked version of the organism's genome. ... The second is to use the entire genome of the organism as the decoy sequence.

Alexander Ross

Alexander Ross

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Alexander Ross has covered the video game industry for a decade, writing deep dives on game design, esports tournaments, VR developments, and gaming culture.