What Is Derived from Pomc
The Pomc Gene Provides Instructions for Making a Protein Called Proopiomelanocortin (Pomc), Which Is Cut (Cleaved) into Smaller Pieces Called Peptides That...
The POMC gene provides instructions for making a protein called proopiomelanocortin (POMC), which is cut (cleaved) into smaller pieces called peptides that have different functions in the body. … One peptide produced from the POMC protein is called adrenocorticotropic hormone (ACTH).
Where is Alpha MSH produced?
Alpha-MSH, β-MSH, and γ-MSH are peptide hormones secreted from melanotropes in the pars intermedia in the pituitary. These peptides are generated from a precursor protein called proopiomelanocortin (POMC), by posttranslational proteolytic cleavage.
Where are POMC neurons?
POMC neuronal cells are mostly located in the hypothalamus and release bioactive molecules (melanocortins) as a result of the post-translational cleavage of POMC, which signals via specialized brain metabolic receptors (melanocortin receptor type 4 (MC4R)) to modulate food intake and systemic energy metabolism2.
Robert Thorne covers electric vehicle innovations, autonomous driving systems, global mobility trends, and automotive engineering developments.
