What Is Drug Response
18.1 Overview. Drug Response or Adverse Effect Is the Net Effect of Multiple Factors: Age, Organ Function, Concomitant Therapy, Drug Interactions, and Disease...
18.1 Overview. Drug response or adverse effect is the net effect of multiple factors: age, organ function, concomitant therapy, drug interactions, and disease.
What are the types of drug response?
Adverse drug reactions are classified into six types (with mnemonics): dose-related (Augmented), non-dose-related (Bizarre), dose-related and time-related (Chronic), time-related (Delayed), withdrawal (End of use), and failure of therapy (Failure).
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How is drug response measured?
The metrics usually used to parameterize drug response (IC50, Emax, or AUC) are based on assessing the cell count of a treated condition relative to an untreated control.
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