What Is Mucin Deposition

Mucin deposition is a common histological finding in patients with CLE, but it is unusual for the mucin to be present in such a quantity to produce detectable skin lesions. The lesions are asymptomatic erythematosus to skin-colored papules and nodules that present on the trunk, arm, head, and neck.

What is mucin in the skin?

Mucins are high-molecular weight glycoproteins typically found in normal skin in small amounts. There are several reports regarding different types of cutaneous mucinosis. In this report, we discuss mucins in dermatopathology as a diagnostic clue of some well-known entities and some less frequent cutaneous diseases.

What causes cutaneous mucinosis?

The cause of cutaneous mucinosis is believed to be an inherited genetic mutation of the Shar Pei breed. One theory suggests that the mucinosis may be due to a higher amount or increased activity of hyaluronic acid, while another theory targets a defect in the metabolism of the carbohydrate.