What Is Mucosal Disruption

Abstract. The gastric mucosal barrier

How is gastric mucosa repaired?

Superficial injury of the gastric mucosa, such as occurs after ethanol or aspirin ingestion, is usually resurfaced in 1 or 2 h. This is accomplished by rapid migration of surface mucous cells to cover the defect, followed by a later increase in cellular proliferation to restore the pits to their original length.

What is mucosal irregularity?

When the gastric mucosa is greatly hypertrophied, the folds on the greater curvature appear thickened, irregular, and spiked, while the spaces between the folds are markedly widened. These enlarged gastric mucosal folds are best seen on the greater curvature; the lesser curvature usually retains its smooth contour.