What Is Neuropathic Itch?

Considered physiologically, neuropathic itch is a pathological form of itch where the stimulus-response curve that governs normal sensation has become distorted and the itch sensation is out of proportion or even completely independent of any pruritogenic stimuli.

What does a neuropathic itch feel like?

A neuropathic itch may produce an itching sensation or a feeling of pins and needles. The itching may be very severe. Neuropathic itch may also produce the following sensations: burning.

What triggers neuropathic itch?

Neuropathic itch occurs due to damage of neurons of the peripheral or central nervous system. Several entities, including metabolic, neurodegenerative, orthopedic, infectious, autoimmune, malignant, and iatrogenic conditions, may affect the somatosensory system and induce neuropathic itch.