What Is Normal Ki67

A result of less than 6% is considered low, 6-10% intermediate, and more than 10% is considered high. Ki-67: Ki-67 is a protein in cells that increases as they prepare to divide into new cells. A staining process can measure the percentage of tumor cells that are positive for Ki-67.

Is Ki67 expression in normal cells?

Ki-67 was first identified via an antibody raised against Hodgkin’s lymphoma cell nuclei (1). Because Ki-67 is generally expressed strongly in proliferating cells and poorly in quiescent cells (2), anti-Ki-67 antibodies are frequently used to detect proliferative cells in clinical studies (3, 4).

What does low Ki67 mean?

In general, if the Ki67 is between 0-2%, then we call it grade 1 or low grade. If it is between 2-20%, we call it grade 2 or intermediate grade. If it is > 20%, then it is grade 3 or high grade. The good, the bad, and the ugly. However, the devil is in the details.

Alexander Ross

Alexander Ross

Gaming, Esports & Interactive Media Writer

Alexander Ross has covered the video game industry for a decade, writing deep dives on game design, esports tournaments, VR developments, and gaming culture.

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