What Is Palmoplantar Keratoderma

Palmoplantar keratoderma (PPK) is a heterogeneous group of inherited or acquired disorders characterized by excessive epidermal thickening of the palms and soles.

What causes Palmoplantar Keratoderma?

There are many possible causes for acquired palmoplantar keratodermas including drugs, menopause, chemicals (e.g. arsenic), mechanical stimulation, malnutrition, systemic conditions (e.g. thyroid disease, circulatory disorders), malignancies (e.g. lung cancer, colon cancer, lymphomas), skin conditions (e.g. psoriasis, …

Is Keratoderma cancerous?

Palmoplantar keratoderma (PPK) is a congenital or acquired disorder characterized by the abnormal thickening of the skin of the palms and soles. The thickening can present as a diffuse, focal or punctate pattern. It has been reported to be associated with internal malignancies such as lung and esophageal carcinomas.