What Is Peptide Mapping

Peptide mapping is a component of the analytical toolbox used within the biopharmaceutical industry to aid in the identity confirmation of a protein therapeutic and to monitor degradative events such as oxidation or deamidation.

What does peptide mapping do?

A peptide map is a fingerprint of a protein and the end product of several processes that provide a comprehensive understanding of the protein being analyzed. … Peptide mapping is considered a comparative procedure that confirms the primary structure of the protein and detects alterations in structure.

How are peptides used in research?

Peptides are used to prepare epitope-specific antibodies, map antibody epitopes and enzyme binding sites and to design novel enzymes, drugs and vaccines.