What Is Physostigmine Used For

Physostigmine salicylate has FDA approval for use in the treatment of glaucoma and the treatment of anticholinergic toxicity. It is useful to treat the central nervous system effects of anticholinergic toxicity due to its ability to cross the blood-brain barrier.

When do you give physostigmine?

Physostigmine treatment may be indicated for patients with moderate to severe anticholinergic poisoning with evidence of both peripheral and central toxicity.

What are the side effects of physostigmine?

• excessive saliva production.
• excessive sweating.
• nausea.
• vomiting.
• diarrhea.
• stomach cramps.