How long should dogs be on proin?

The dogs were given Proin ER for 28 days. Their owners noted how many accidents the dogs had each day. After four weeks, 75 of the 104 dogs who completed the study had no accidents on either tablet.

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Can proin cause kidney failure in dogs?

Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. In some cases, death, including euthanasia, has been reported.