What Is Red Cell Aplasia
Pure Red Cell Aplasia (Prca) Is a Rare Disorder of Blood Production in Which the Bone Marrow, the Spongy Tissue in the Center of the Bones, Fails to Function...
Pure red cell aplasia (PRCA) is a rare disorder of blood production in which the bone marrow, the spongy tissue in the center of the bones, fails to function in an adequate manner resulting in anemia. Red blood cells are responsible for carrying oxygen to the entire body.
Is pure red cell aplasia a cancer?
The “pure” red cell aplasia, Diamond Blackfan anemia, felt by many to be the “sine qua non” of pediatric hematology, is one of a rare group of inherited bone marrow failure syndromes (IBMFS) distinguished by the variable presence of congenital anomalies and a predisposition to cancer.
Must Read
How is PRCA diagnosed?
The diagnosis of PRCA is based on the absence or near absence of erythroblasts from an otherwise normal marrow (<1% erythroblasts on the marrow differential count). In some cases, a few proerythroblasts and/or basophilic erythroblasts are seen, not exceeding 5% of the differential count.