What Is Rps Blast
Rps-Blast (Reverse Psi-Blast) Searches a Query Sequence Against a Database of Profiles. This Is the Opposite of Psi-Blast That Searches a Profile Against a...
RPS-BLAST (Reverse PSI-BLAST) searches a query sequence against a database of profiles. This is the opposite of PSI-BLAST that searches a profile against a database of sequences, hence the ‘Reverse’. … RPS-BLAST was coded by Sergei Shavirin with some help from Tom Madden.
RPS-BLAST is a variant of the PSI-BLAST program. Whereas PSI-BLAST first builds a PSSM that is used as a query for subsequent database searches, RPS-BLAST uses a protein sequence query to search a database of precalculated PSSMs in a single pass.
How does Basic Local Alignment Search Tool Work?
The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.