What Is Th1 Dominance
Th1 and Th2 Cells Are Known to Antagonize Each Other in a Variety of Ways [18, 19], and Several Chronic Inflammatory Autoimmune Diseases Such as Multiple...
Th1 and Th2 cells are known to antagonize each other in a variety of ways [18, 19], and several chronic inflammatory autoimmune diseases such as multiple sclerosis (MS), diabetes and rheumatoid arthritis (RA) have been described as Th1 dominant diseases [20], while atopy and allergy are Th2 dominant diseases [21].
What are Th1 diseases?
Th1 cells are involved in the pathogenesis of organ-specific autoimmune disorders, Crohn’s disease, Helicobacter pylori-induced peptic ulcer, acute kidney allograft rejection, and unexplained recurrent abortions.
What is Th1 function?
The main effector functions of Th1 cells are in cell-mediated immunity and inflammation, including the activation of cytolytic and other effector functions of other immune cells such as macrophages, B cells, and CD8+ cytotoxic T lymphocytes (CTLs).
Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.
